Bifidobacterium breve

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This strain of bacteria helps increase weight gain in infants, iron absorption, and reduces associated symptoms of IBS

Bifidobacterium Breve is normal flora that can be found throughout the digestive tract and vagina.

Research links this bacteria with reducing yeast infections in women[1], enhancing the intestinal immune system[2], aiding in the prevention of rotavirus infection[3], and assists to increase weight gain in underweight infants by promoting normal bacteria in their bowel.[4]. This bacteria also aids in improving gut colonization and pathogen protection which can also increase iron absorption in the gut[5]†.  Bifidobacterium breve aids in increasing regulatory T cell responses which helps reduce Irritable Bowel Syndrome[6]†. In addition, this bacteria prevents the stimulation of pathogens that could cause harm in the gut[7]†, and has shown to have good bile tolerance which can help improve its colonization in the gut[8].

[1] Effects of probiotic bacteria on Candida presence and IgA anti-Candida in the oral cavity of elderly. Braz Dent J. 2012;23(5):534-8.

[2] Ciprandi, G., A. Scordamaglia, D. Venuti, M. Caria, and G. W. Canonica. (1986). "In vitro effects of Bacillus subtilis on the immune response". Chemioterapia 5 (6): 404–7. PMID 3100070.

[3] Araki, K. et al. Trial of oral administration of Bifidobacterium breve for the prevention of rotavirus infections.  Kansenshogaku Zasshi, 73,305,1999. 

[4] Kitajima H, Sumida Y, Tanaka R, Yuki N, Takayama H, Fujimura M. Early administration of Bifidobacterium breve to preterm infants: randomised controlled trial. Archives of Disease in Childhood Fetal and Neonatal Edition1997;76(2):F101-F107. 

[5] Christiaen SEA, O’Connell Motherway M, Bottacini F, et al. Autoinducer-2 Plays a Crucial Role in Gut Colonization and Probiotic Functionality ofBifidobacterium breve UCC2003. Riedel CU, ed. PLoS ONE 2014;9(5):e98111. doi:10.1371/journal.pone.0098111. 

[6] Zheng B, van Bergenhenegouwen J, Overbeek S, et al. Bifidobacterium breveAttenuates Murine Dextran Sodium Sulfate-Induced Colitis and Increases Regulatory T Cell Responses. Fuss IJ, ed. PLoS ONE 2014;9(5):e95441. doi:10.1371/journal.pone.0095441. 

[7] Fanning S, Hall LJ, Cronin M, et al. Bifidobacterial surface-exopolysaccharide facilitates commensal-host interaction through immune modulation and pathogen protection. Proceedings of the National Academy of Sciences of the United States of America 2012;109(6):2108-2113. doi:10.1073/pnas.1115621109.

[8]Ruiz L, O’Connell‐Motherway M, Zomer A, de los Reyes‐Gavilán CG, Margolles A, van Sinderen D. A bile‐inducible membrane protein mediates bifidobacterial bile resistance. Microbial biotechnology 2012;5(4):523-535. doi:10.1111/j.1751-7915.2011.00329.x. 

Probiotics containing Bifidobacterium Breve: 

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